Mohammed Gharaibeh
Associate Professor of Physical Chemistry
Mohammed Gharaibeh
Associate Professor of Physical Chemistry
Affiliation
The University of Jordan, Amman, Jordan
Education
- Ph.D., Physical Chemistry, University of Kentucky, USA
- M.S., Physical Chemistry, The University of Jordan, Jordan
- B.S., Chemistry, Yarmouk University, Jordan
Academic Biography
Education
Dr. Mohammed Gharaibeh earned his Ph.D. in Physical Chemistry from the University of Kentucky in 2012, following an M.S. in Chemistry from the University of Jordan in 1999 and a B.S. in Chemistry from Yarmouk University in 1996.
Postdoctoral Training
In 2017, Dr. Gharaibeh completed postdoctoral research in molecular spectroscopy as a Fulbright Visiting Scholar at the University of Kentucky.
Academic Appointments
Dr. Gharaibeh has been an Associate Professor of Physical Chemistry at the University of Jordan since 2013. His previous experience includes teaching and research positions at the University of Jordan and the University of Kentucky, as well as research and development in the pharmaceutical industry.
Research Focus
Dr. Gharaibeh's research focuses on physical chemistry and molecular spectroscopy, particularly the spectroscopic characterization of transient molecules, molecular structure and dynamics, and the application of advanced spectroscopic techniques. He is also actively engaged in student mentorship and international research collaboration.
Research Interests
- Spectroscopy of Intermediate Molecules
- Theoretical and Computational Chemistry
- Renner-Teller Effect in Triatomic Mmolecules
Dr. Mohammed A. Gharaibeh's research spans physical chemistry, molecular spectroscopy, theoretical and computational chemistry, and computational drug discovery. His work integrates experimental and computational approaches to investigate molecular structure, dynamics, and reactivity, with particular emphasis on transient molecules and the Renner–Teller effect in triatomic systems.
His research has advanced the spectroscopic detection and characterization of transient molecular species, including gas-phase stannylidene (H₂C=Sn and D₂C=Sn), contributing to a deeper understanding of molecular structure, reaction mechanisms, and vibronic interactions. His studies of the Renner–Teller effect have provided valuable insights into the electronic structure and energy-level splitting of linear triatomic molecules.
Dr. Gharaibeh also applies density functional theory (DFT) and time-dependent density functional theory (TD-DFT) to investigate molecular properties and excited-state phenomena. His computational studies of BODIPY dyes have contributed to the rational design of materials for dye-sensitized solar cells (DSSCs) and other photonic applications.
More recently, his research has expanded into computational biochemistry and computer-aided drug discovery, employing molecular docking, molecular dynamics simulations, and related computational methods to investigate natural products and biologically relevant proteins. His work includes studies on the therapeutic potential of Ephedra alte constituents against inflammatory targets and the structural and dynamical effects of mutations in the tumor suppressor protein p53, with applications in cancer research.
Through an interdisciplinary research program, Dr. Gharaibeh continues to advance the understanding of molecular systems while contributing to applications in spectroscopy, materials science, and biomedical research.
Publications
Peer-Reviewed Articles
- Salman HA, Yaakop AS, Aladaileh S, Mustafa M, Gharaibeh M, Kahar UM. Inhibitory effects of Ephedra alte on IL-6, hybrid TLR4, TNF-α, IL-1β, and extracted TLR4 receptors: in silico molecular docking. Heliyon. 2022 Dec 30;9(1):e12730. https://linkinghub.elsevier.com/retrieve/pii/S240584402204018X
- W. Helal, A. Marashdeh, Q. Alkhatib, H. Qashmar, M. Gharaibeh, A. T. Afaneh. Tuning the photophysical properties of BODIPY dyes used in DSSCs as predicted by double-hybrid TD-DFT: The role of the methyl substituents. Int. J. Quantum Chem. 2022, 122(24), e27000. https://onlinelibrary.wiley.com/doi/10.1002/qua.27000
- Smith TC, Gharaibeh M, Clouthier DJ. Spectroscopic detection of the stannylidene (H2C=Sn and D2C=Sn) molecule in the gas phase. J Chem Phys. 2022 Nov 28;157(20):204306. https://pubs.aip.org/jcp/article/157/20/204306/2842261/Spectroscopic-detection-of-the-stannylidene-H2C-Sn
- Mustafa, Morad; Gharaibeh, Mohammad. Most Probable Druggable Pockets in Mutant p53-Arg175His Clusters Extracted from Gaussian Accelerated Molecular Dynamics Simulations. Protein Journal. 2022; 41:27–43. https://link.springer.com/article/10.1007/s10930-022-10041-0?error=cookies_not_supported&code=29de6ac5-2f13-4dca-8ec1-7db66cf24b2b
- Wissam Helal, Qabas Alkhatib, Mohammed Gharaibeh. Can time-dependent double hybrid density functionals accurately predict electronic excitation energies of BODIPY compounds? Computational and Theoretical Chemistry. Volume 1207, 2022, 113531. https://linkinghub.elsevier.com/retrieve/pii/S2210271X21003893
- Mustafa, Morad; Wedian, Fadel; Aldal’in, Hammad K.; Al-Mazaideh, Ghassab M.; Mahmoud, Sabry Younis; Farrag, Eman Saleh; Gharaibeh, Mohammed; Hijawi, Thameen; Al-Rimawi, Fuad; Abbadi, Jehad; Shalayel, Mohammed Helmy Faris; Siddique, Nadeem A.; Salman, Haya Ayyal; Huneif, Mohammed Ayed. The efficiency of some active ingredients of Arum Palaestina as inhibitors to 3CLpro and Nsp15 proteins. Acta Poloniae Pharmaceutica – Drug Research. 2021;78(5):657–665.
- Mohammed Gharaibeh, Bayenah Al-Shami, Wissam Helal. Electronic spectrum of boron dichloride. theoretical study of vibronic levels of the ground and first excited states. Journal of Molecular Structure. Volume 1224, 2021, 129206. https://linkinghub.elsevier.com/retrieve/pii/S002228602031526X
- Deeb Taher, Sami Klaib, Firas F. Awwadi, Wissam Helal, Mohammed Gharaibeh, Gerd Rheinwald, Tobias Rüffer, Heinrich Lang. Ti(ƞ5-1-SiMe3-C9H6)(Cl)2(OR): Structure and bonding. Inorganica Chimica Acta. Volume 477, 2018, Pages 270-276. https://linkinghub.elsevier.com/retrieve/pii/S0020169318301099
- Gharaibeh M, Clouthier DJ, Tarroni R. An experimental and theoretical study of the Ã(2)A(″)Π-X̃(2)A(‘) band system of the jet-cooled HBBr/DBBr free radical. J Chem Phys. 2016 Jun 21;144(23):234309. https://pubs.aip.org/jcp/article/144/23/234309/281150/An-experimental-and-theoretical-study-of-the-A-2A
- Sunahori FX, Gharaibeh M, Clouthier DJ, Tarroni R. BH2 revisited: New, extensive measurements of laser-induced fluorescence transitions and ab initio calculations of near-spectroscopic accuracy. J Chem Phys. 2015 May 7;142(17):174302. https://pubs.aip.org/jcp/article/142/17/174302/940363/BH2-revisited-New-extensive-measurements-of-laser
- Gharaibeh MA, Nagarajan R, Clouthier DJ, Tarroni R. An experimental and theoretical study of the electronic spectrum of the HBCl free radical. J Chem Phys. 2015 Jan 7;142(1):014305. https://doi.org/10.1063/1.4904892
Conferences, Symposiums, and Workshops
- Mohammed Gharaibeh, The 16th Jordanian Chemistry Conference-Five Decades In Chemistry, The University of Jordan, Amman, Jordan, 2019.
- Tony Smith; Mohammed Gharaibeh; Dennis Clouthier, International Symposium on Molecular Spectroscopy, Urbana-Champaign, Illinois, USA, 2018.
- Mohammed Gharaibeh, The 1st International Conference on Natural Products and Drug Discovery, The University of Jordan, Amman, Jordan, 2015.
- Mohammed Gharaibeh; Fumie X Sunahori; Dennis Clouthier, 69th International Symposium on Molecular Spectroscopy, Columbus, Ohio, USA, 2014.